Carbohydrate-coated nanocapsules from amphiphilic rod-coil molecule: binding to bacterial type 1 pili.
نویسندگان
چکیده
Stable carbohydrate-coated nanocapsules designed as multivalent nanoscaffolds for selective interactions with receptors are able to encapsulate guest molecules within their interior and to bind efficiently to FimH adhesin of bacterial type 1 pili.
منابع مشابه
Controlled self-assembly of carbohydrate conjugate rod-coil amphiphiles for supramolecular multivalent ligands.
Carbohydrate conjugate rod-coil amphiphiles were synthesized and their self-assembling behavior in aqueous solution was investigated. These amphiphiles were observed to self-assemble into supramolecular structures that differ significantly depending on the molecular architecture. The rod-coil amphiphiles based on a short coil (1) self-assemble into a vesicular structure, while the amphiphiles w...
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ورودعنوان ژورنال:
- Chemical communications
دوره 15 شماره
صفحات -
تاریخ انتشار 2005